abstract：BACKGROUND:Mental disorders often begin during the formative years of education. They may disrupt education and lead to social underachievement. METHODS:We examined the impact of mental disorders treated in hospital (ages 16-29) on educational attainment up to 31 years in the Northern Finland 1966 Birth Cohort (N = 10...

journal_title：Psychological medicine

authors： Isohanni I,Jones PB,Järvelin MR,Nieminen P,Rantakallio P,Jokelainen J,Croudace TJ,Isohanni M

更新日期：2001-02-01 00:00:00

abstract：BACKGROUND:A number of studies have suggested that indirect semantic priming is enhanced in thought-disordered schizophrenics. However, research on direct semantic priming has produced conflicting results. The aim of the present study was to resolve some of the ambiguities of previous findings. METHODS:For the present...

journal_title：Psychological medicine

authors： Moritz S,Mersmann K,Kloss M,Jacobsen D,Wilke U,Andresen B,Naber D,Pawlik K

更新日期：2001-02-01 00:00:00

abstract：BACKGROUND:Depressive syndromes not fulfilling the criteria for specified disorders (subthreshold depression, SD) may be clinically important. We aimed to study SD in old and very old age, in comparison with subjects with no depressive symptoms (NDS) and subjects with major depression (MD). METHODS:A community-based r...

journal_title：Psychological medicine

authors： Geiselmann B,Linden M,Helmchen H

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:A previous study of women 9 months after discharge from in-patient treatment for depression found that low self-esteem as measured by a self-report questionnaire at admission was associated with a worse prognosis. This study investigates the womens' outcome more than 4 years after discharge and the continued...

journal_title：Psychological medicine

authors： Sherrington JM,Hawton K,Fagg J,Andrew B,Smith D

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:A combined family study and recovered study design was utilized to examine several hypothesized relationships between personality and bulimia nervosa (BN). METHODS:We studied 47 women with a lifetime history of DSM-III-R BN (31 currently ill and 16 recovered), 44 matched control women (CW) with no history o...

journal_title：Psychological medicine

authors： Lilenfeld LR,Stein D,Bulik CM,Strober M,Plotnicov K,Pollice C,Rao R,Merikangas KR,Nagy L,Kaye WH

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:We examined the relationship between childhood sexual abuse (CSA), and interviewees' recollections of pathogenic parenting, testing for possible retrospective biases in the recollections of those who have experienced CSA. METHODS:Information about CSA, parental divorce and interviewees' recollections of par...

journal_title：Psychological medicine

authors： McLaughlin TL,Heath AC,Bucholz KK,Madden PA,Bierut LJ,Slutske WS,Dinwiddie S,Statham DJ,Dunne MP,Martin NG

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:High expressed emotion (EE) in families reliably predicts relapse in schizophrenia leading to the assumption that high EE stresses patients and is the cause of relapse. Attempts at validating the stressful properties of high EE using autonomic skin conductance measures have been inconclusive. Since memory lo...

journal_title：Psychological medicine

authors： Dixon MJ,King S,Stip E,Cormier H

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:Although the traditional view of bipolar affective disorder is that the majority of patients have full remission between episodes, recent evidence suggests that residual cognitive deficits are present. The aim of this study was to determine whether memory and executive deficits were present in a well-defined...

journal_title：Psychological medicine

authors： Rubinsztein JS,Michael A,Paykel ES,Sahakian BJ

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:Hip fracture is common in the elderly. Previous studies suggest that psychiatric illness is common and predicts poor outcome, but have methodological weaknesses. Further studies are required to address this important issue. METHODS:We prospectively recruited 731 elderly participants with hip fracture in two...

journal_title：Psychological medicine

authors： Holmes J,House A

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:Different versions of the General Health Questionnaire (GHQ), including the GHQ-12 and GHQ-28 have been subjected to factor analysis in a variety of countries. The World Health Organization study of psychological disorders in general health care offered the opportunity to investigate the factor structure of ...

journal_title：Psychological medicine

authors： Werneke U,Goldberg DP,Yalcin I,Ustün BT

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:Few population studies have investigated the functional disabilities that accompany specific psychiatric diagnoses. This study assesses the nature and strength of current and residual impairments in various functional domains of life. METHODS:Data were derived from the Netherlands Mental Health Survey and I...

journal_title：Psychological medicine

authors： Bijl RV,Ravelli A

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND:The importance of genetic factors in the aetiology of manic-depressive illness (MDI) has been repeatedly confirmed and indicators of vulnerability to the illness in families with affective disorders are needed. Abnormal event-related potentials (ERP) may be markers of genetic vulnerability to mental illness....

journal_title：Psychological medicine

authors： Pierson A,Jouvent R,Quintin P,Perez-Diaz F,Leboyer M

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND:There is not yet consensus on the best diagnostic definition of mixed bipolar episodes. Many have suggested the DSM-III-R/-IV definition is too rigid. We propose alternative criteria using data from a large patient cohort. METHODS:We evaluated 237 manic in-patients using DSM-III-R criteria and the Scale for...

journal_title：Psychological medicine

authors： Cassidy F,Ahearn E,Murry E,Forest K,Carroll BJ

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:Based on the developing clinical and legal literature, and using the framework adopted in draft legislation, capacity to make a valid decision about a clinically required blood test was investigated in three groups of people with a 'mental disability' (i.e. mental illness (chronic schizophrenia), 'learning d...

journal_title：Psychological medicine

authors： Wong JG,Clare CH,Holland AJ,Watson PC,Gunn M

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:Expressed emotion (EE) measured from relatives and informal carers has been consistently demonstrated to be associated with clinical outcome in schizophrenic patients. There have also been published studies that have investigated EE in professional carers that have suggested that the quality of the relations...

journal_title：Psychological medicine

authors： Tattan T,Tarrier N

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Quetiapine (ICI 204,636, 'Seroquel') is a new atypical antipsychotic agent with a similar binding profile to the original atypical antipsychotic, clozapine. Its clinical efficacy has already been demonstrated at multiple fixed doses (150-750 mg/day) and has been suggested to be comparable with haloperidol (1...

journal_title：Psychological medicine

authors： Copolov DL,Link CG,Kowalcyk B

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Recent studies have suggested that major depressive disorders are associated with a breakdown in the organization of ultradian rhythm in sleep EEG. The present study used cross-spectral analysis of sleep EEG to confirm this finding, in a larger-scale study, evaluating the influence of gender and age on ultra...

journal_title：Psychological medicine

authors： Armitage R,Hoffmann RF,Rush AJ

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND:The reasons for high use of primary care, and in particular the role of psychosocial factors, remain unclear. METHODS:We identified and interviewed 236 frequent attenders and 420 normal users, matched by age and sex, of a public Health Centre in Granada, Spain. Users were questioned about mental health (GHQ...

journal_title：Psychological medicine

authors： Bellón JA,Delgado A,Luna JD,Lardelli P

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND:The effectiveness of therapeutic interventions in psychosis is increasingly reported in terms of reductions in different symptom dimensions. It remains unclear, however, to what degree such symptomatic changes are accompanied by improvement in other measures such as service use, quality of life, and needs fo...

journal_title：Psychological medicine

authors： van Os J,Gilvarry C,Bale R,van Horn E,Tattan T,White I,Murray R

更新日期：1999-09-01 00:00:00

abstract：BACKGROUND:It is clearly established that emotional events tend to be remembered particularly vividly. The neurobiological substrates of this phenomenon are poorly understood. Recently, the noradrenergic system has been implicated in that beta blockade has been shown to reduce significantly the delayed recall of emotio...

journal_title：Psychological medicine

authors： O'Carroll RE,Drysdale E,Cahill L,Shajahan P,Ebmeier KP

更新日期：1999-09-01 00:00:00

abstract：BACKGROUND:Empirical data regarding prevalence of sexual and physical abuse histories in Japanese patients with eating disorders is lacking, in contrast to Western countries. This study investigated the prevalence of traumatic events in Japanese patients with eating disorders, and examined the relationship between such...

journal_title：Psychological medicine

authors： Nagata T,Kiriike N,Iketani T,Kawarada Y,Tanaka H

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND:We developed a comprehensive, 20-hour training programme for primary-care physicians, that sought to improve their ability to detect, diagnose and manage depression. We evaluated the effects of physician training on patient outcomes, using a pre-post design. METHODS:In the pre-training phase of the study, w...

journal_title：Psychological medicine

authors： Tiemens BG,Ormel J,Jenner JA,van der Meer K,Van Os TW,van den Brink RH,Smit A,van den Brink W

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND:There are considerable differences between and within countries in the involvement of general practitioners (GPs) in psychosocial care. This study aimed to describe the self-perceived role of GPs in 30 European countries as the first contacted professional for patients with psychosocial problems. and to exam...

journal_title：Psychological medicine

authors： Boerma WG,Verhaak PF

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND:The usefulness of any diagnostic scheme is directly related to its ability to provide clinically useful information on need for care. In this study, the clinical usefulness of dimensional and categorical representations of psychotic psychopathology were compared. METHOD:A total of 706 patients aged 16-65 ye...

journal_title：Psychological medicine

authors： Van Os J,Gilvarry C,Bale R,Van Horn E,Tattan T,White I,Murray R

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND:We studied whether heterogeneous profiles of cognitive function are relevant to survival in patients with early Alzheimer's disease. METHODS:CAMCOG subscales of cognitive function were used as predictors of survival, together with gender in 157 consecutively referred patients with early Alzheimer's disease....

journal_title：Psychological medicine

authors： Claus JJ,Walstra GJ,Bossuyt PM,Teunisse S,Van Gool WA

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND:Physical symptoms are commonly presented for treatment in the absence of physical pathology. This study tests predictions arising from the theory that childhood sexual abuse leads to emotional distress, illness orientation and social dysfunction as adults and that one or more of these effects, in turn, leads...

journal_title：Psychological medicine

authors： Reilly J,Baker GA,Rhodes J,Salmon P

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND:Chronic fatigue syndrome (CFS) patients often complain that they are more susceptible to acute mental fatigue. It is important to determine whether this is observed using objective tests of sustained attention and responding. METHODS:Sixty-seven patients who fulfilled the criteria for CFS proposed by Sharpe...

journal_title：Psychological medicine

authors： Smith AP,Borysiewicz L,Pollock J,Thomas M,Perry K,Llewelyn M

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND:Current mental health legislation in the UK makes provision for the use of certain treatments in severely ill patients who are unable, or unwilling, to give informed consent. Under the terms of this legislation, electroconvulsive therapy (ECT) may be used, usually to treat severely depressed patients. A numb...

journal_title：Psychological medicine

authors： Wheeldon TJ,Robertson C,Eagles JM,Reid IC

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Breathlessness in asthma often cannot be explained with objective variables indicating airways obstruction. The hypothesis that unrealistic breathlessness results from false interpretation of sensations was tested. METHODS:Sixty-four children and adolescents with asthma, aged 9-18 years, were randomly assig...

journal_title：Psychological medicine

authors： Rietveld S,Everaerd W,Vanbeest I

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:The treatment of deliberate self-harm (parasuicide) remains limited in efficacy. Despite a range of psychosocial, educational and pharmacological interventions only one approach, dialectical behaviour therapy, a form of cognitive-behaviour therapy (CBT), has been shown to reduce repeat episodes, but this is ...

journal_title：Psychological medicine

authors： Evans K,Tyrer P,Catalan J,Schmidt U,Davidson K,Dent J,Tata P,Thornton S,Barber J,Thompson S

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Previous studies on assortment for psychiatric disorders have reported discrepant findings. We aimed to test whether there is a significant association for psychiatric diagnoses, including alcoholism, generalized anxiety disorder, major depressive disorder, panic disorder and phobias between husbands and wiv...

journal_title：Psychological medicine

authors： Maes HH,Neale MC,Kendler KS,Hewitt JK,Silberg JL,Foley DL,Meyer JM,Rutter M,Simonoff E,Pickles A,Eaves LJ

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND:Life events and social problems are common in primary-care attenders and contribute to the high rate of emotional distress observed in this setting but are often not disclosed during the consultation. Physicians' characteristics associated with patients' disclosure of psychosocial problems are well documente...

journal_title：Psychological medicine

authors： Del Piccolo L,Saltini A,Zimmermann C

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND:Recent anthropological studies have documented the importance of understanding the relation of culture to the experience of mental illness. The use of interviews that elicit explanatory models has facilitated such research, but currently available interviews are lengthy and impractical for epidemiological st...

journal_title：Psychological medicine

authors： Lloyd KR,Jacob KS,Patel V,St Louis L,Bhugra D,Mann AH

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND:We report the prevalence, clinical characteristics, frequency of mental health treatment, demographic correlates, frequency of co-morbid psychiatric conditions, and general health ramifications of DSM-IV blood-injection-injury phobia in the general population. METHOD:The Diagnostic Interview Schedule (versi...

journal_title：Psychological medicine

authors： Bienvenu OJ,Eaton WW

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND:A review of studies of cognition in the euthymic phase of unipolar and bipolar affective disorder reveals diverging results. METHODS:The study was designed as a controlled cohort study, with the Danish psychiatric case register of admissions used to identify patients and the Danish civil register to identif...

journal_title：Psychological medicine

authors： Kessing LV

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND:The aims of the present study were to examine serum activities of peptidases, i.e. prolyl endopeptidase (PEP) and dipeptidyl peptidase IV (DPP IV), in patients with fibromyalgia and to examine the effects of subchronic treatment with sertraline on these variables. METHOD:Serum PEP and DPP IV activity were m...

journal_title：Psychological medicine

authors： Maes M,Libbrecht I,Van Hunsel F,Lin AH,Bonaccorso S,Goossens F,De Meester I,De Clerck L,Biondi M,Scharpe S,Janca A

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND:Psychiatric history, familial history of suicide attempts, and certain traumatic life events are important predictors of suicidal thoughts and behaviour. We examined the epidemiology and genetics of suicidality (i.e. reporting persistent suicidal thoughts or a plan or suicide attempt) in a large community-ba...

journal_title：Psychological medicine

authors： Statham DJ,Heath AC,Madden PA,Bucholz KK,Bierut L,Dinwiddie SH,Slutske WS,Dunne MP,Martin NG

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND:Although many case-control studies have replicated an association between dysfunctional parenting and a lifetime diagnosis of depression, few epidemiological studies have explored the association. In addition, little is known about the association in non-western countries. METHODS:Using logistic regression ...

journal_title：Psychological medicine

authors： Sato T,Sakado K,Uehara T,Narita T,Hirano S,Nishioka K,Kasahara Y

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND:Substantial variability in age at onset of illness and course of illness exists between patients with schizophrenia. Recent studies suggest that age at illness onset may be useful in defining biologically and clinically distinct subgroups of patients. METHODS:Two hundred and ten males with schizophrenia wer...

journal_title：Psychological medicine

authors： Smith GN,Kopala LC,Lapointe JS,MacEwan GW,Altman S,Flynn SW,Schneider T,Falkai P,Honer WG

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND:The methodology for measuring the needs of patients with severe mental illness is now well established through the MRC Needs for Care Assessment Schedule and its modification in the form of the Cardinal Needs Assessment. This paper reports the rationale and construction of a relatives' version of the Cardina...

journal_title：Psychological medicine

authors： Barrowclough C,Marshall M,Lockwood A,Quinn J,Sellwood W

更新日期：1998-05-01 00:00:00